Myocardial Infarction in Patients with and without COVID-19: Comparisons of Characteristics, Clinical Courses, and Outcomes.

Background: COVID-19 has rapidly become a global health emergency. This infection can cause damage to various organs. Injury to myocardial cells is one of the salient manifestations of COVID-19. The clinical course and outcome of acute coronary syndrome (ACS) are influenced by various factors, including comorbidities and concomitant diseases. One of these acute concomitant diseases is COVID-19, which can affect the clinical course and outcome of acute myocardial infarction (MI). Methods: The present cross-sectional study compared the clinical course and outcome of MI and some of its practical factors between patients with and without COVID-19. The study population consisted of 180 patients (129 males and 51 females) diagnosed with acute MI. Eighty patients had COVID-19 infection concurrently. Results: The mean age of the patients was 65.62 years. The frequencies of non-ST-elevation MI (vs ST-elevation MI), lower ejection fractions (<30), and arrhythmias were significantly higher in the COVID-19 group than in the non-COVID-19 group (P=0.006, 0.003, and P<0.001, respectively). The single-vessel disease was the most frequent angiographic result in the COVID-19 group, while the double-vessel disease was the most frequent angiographic result in the non-COVID-19 group (P<0.001). Conclusion: It appears that patients with ACS who are co-infected with COVID-19 infection need essential care.

A case of Co-infection COVID-19 and influenza with psychotic symptoms.

Coronavirus disease 2019 (COVID-19), is a pandemic disease that has appeared in recent years with different symptoms and manifestations. This disease has Co-infection with other infections and has aggravated the symptoms in patients. This study was conducted with the aim of reporting a case of Co-infection COVID-19 and influenza with psychotic symptoms. In this study, the manifestations of a case of co-infection with COVID-19 and influenza with psychotic symptoms were discussed in Shahroud city in Iran in 2022. Based on this, the patient's laboratory, pathological and therapeutic findings were investigated. The patient, a 16-year-old boy, had symptoms of fever, chills, cough, body pain, and headache with seizures and delirium. Reverse transcription-polymerase chain reaction tests for covid-19 and influenza were positive, but no abnormalities were observed in laboratory variables and graphs. The patient was treated for psychotic disorders for 40 days and then recovered.

Risk Factors Associated with Mortality in COVID-19 Patient’s: Survival Analysis

Background: The effect of related factors on recovery or death rates may vary from country to country. Therefore, we aimed to investigate the relationship between demographic, clinical, laboratory factors on the survival rates of confirmed cases of COVID-19 in Shahroud, Iran. Methods: This is an analytical study of the estimation of the survival of patients with COVID-19. Patients who had positive PCR test were considered as COVID-19 cases, and the 2-month survival of these patients was estimated. Among the diseases, heart disease and diabetes were considered as separate variables, and the patients’ histories of other diseases were included in the model as comorbidities. Results: Of 396 confirmed patients hospitalized, 109 patients (27.5%) had a history of heart disease, 100 (25.3%) were diabetic, and 80 (20.2%) had a history of other comorbidities. The number of deaths due to the disease was 59 (14.9%). The median age of those who died was 76 years. The multivariate Cox regression analysis shows that heart disease increases hazard ratio more than two times (HR=2.37, 95% CI: 1.33–4.23). The neutrophil-to-lymphocyte ratio (NLR) factor, (HR=1.15, 95% 1.08–1.22), and older age (HR=1.06, 95% CI: 1.03–1.08) increases the risk of death significantly. Conclusion: The heart disease history, NLR factor and older age are associated with death of COVID-19 and may be helpful for the early warning and prediction of disease progression.

Predictors of Self-Reported Compliance with COVID-19 Preventive Guidelines: A Quantile Regression Model.

The research used an online, convenience cross-sectional sample of adults aged ≥18 years old recruited from Shahroud County, Northeast of Iran. We measured the contribution of multiple determinants for association with behavioral compliance, at the time of the COVID-19 pandemic. The compliance score measured with this questionnaire can be within a range of 5 and 100. Compliance was bounded between 19 and 80 that has been distributed J-shape, so quantile logistic regression model has been fitted for that. Variables related to people's knowledge, including self-reported knowledge and following the news related to COVID-19, were the two main factors that accompanied behavioral compliance at all of its levels in the period of pandemic.

Prevalence of Influenza Among Hajj Pilgrims: A Systematic Review and Meta-Analysis.

OBJECTIVES: Respiratory transmission, especially in mass gatherings, is considered one of the main ways of influenza transmission. The Hajj ceremony, as one of the largest gatherings worldwide, can increase the distribution of influenza infection. Thus, the present study aimed to evaluate the incidence of influenza among Hajj pilgrims. METHODS: In this present systematic review and meta-analysis, all English studies published by 2019 were extracted from several databases such as the Web of Science, PubMed, Scopus, Cochrane Library, Science Direct, and Google Scholar. Finally, the data were extracted using a pre-prepared checklist and then analyzed by fixed and random effects model tests in the meta-analysis, Cochran, meta-regression, and Begg's test. RESULTS: Eighteen studies with a sample size of 62 431 were entered into the meta-analysis process. The overall prevalence of influenza, in addition to the prevalence of types A, B, and C influenza, was estimated at 5.9 (95% CI: 4.3-8.0), 3.6 (95% CI: 2.6-4.9), 2.9 (95% CI: 2.8-3.1), and 0.9% (95% CI: 0.5-1.5), respectively. CONCLUSIONS: In general, influenza remains widespread regardless of vaccinating pilgrims and following health protocols. Therefore, it is recommended that comprehensive management and educational approaches be used to reduce the prevalence of influenza and its adverse consequences among the pilgrims.

Effects of the COVID-19 Pandemic on the Intimate Partner Violence and Sexual Function: A Systematic Review.

INTRODUCTION: The pandemic caused by severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), or coronavirus disease 2019 (COVID-19), has affected many people in the world and has impacted the physical, social, and mental health of the world population. One of these psychological consequences is intimate partner violence affecting sexual health. METHODS: This study was performed as a systematic review on the effect of the SARS-CoV-2 pandemic on sexual function and domestic violence in the world. Accordingly, all English-language studies conducted from the beginning of the SARS-CoV-2 pandemic to the end of 2020 were extracted by searching in the Scopus, Web of Science, PubMed (including Medline), Cochrane Library, and Science Direct databases and then reviewed. The quality of the articles was assessed using the STROBE checklist. RESULTS: A total of 11 studies were included in the systematic review. Accordingly, domestic violence during the exposure to COVID-19 had increased. Moreover, the mean scores of sexual function and its components had reduced at the time of exposure to the pandemic compared to before. CONCLUSION: Given the potential long-term effects of the coronavirus crisis and the large population being affected by this disease, strategies to promote sexual health and fertility of families to prevent or further reduce violence and sexual functions should be chosen.

Myocardial Infarction in Patients with and Without Covid-19: Comparison of Characteristics, Clinical Course and Outcome (preprint)

Background: Covid-19 has quickly become a global health emergency. This infection can cause damage to various organs. Injury to myocardial cells is one of the most important manifestations of Covid-19. The clinical course and outcome of Acute Coronary Syndrome (ACS) are influenced by a variety of factors, including comorbidities and concomitant diseases. One of these acute concomitant diseases is Covid-19 which can affect the clinical course and outcome of acute Myocardial Infarction (MI). Methods In this cross-sectional study, the clinical course and outcome of MI and some of its effective factors in patients with and without Covid-19 were compared. 180 patients (129 males and 51 females) with the diagnosis of acute MI were included in the study. 80 patients of them had Covid-19 infection at the same time. Results Increase rate in creatinine, arrhythmia, and need for CPR (cardiopulmonary resuscitation) was significantly higher in the Covid-19 group (p value in all three cases 

More reliability of suspicious symptoms plus chest CT-scan than RT_PCR test for the diagnosis of COVID-19 in an 18-days-old neonate.

The present study investigated an 18-days-old neonate who was referred to the hospital with suspected respiratory symptoms of COVID-19. Results of CT-Scan and blood tests were highly suspicious, but result of the first RT-PCR test was negative on March 1. The second RT-PCR test reported positive on March 12. The neonate's medical history indicated no close contact except with family members and hospital treatment staffs, but the RT-PCR test results of all family members were also negative.